How to Build a Skincare Routine That Actually Works: An Evidence-Based Guide

Learn the proven steps to build a skincare routine that actually works. Get dermatologist-backed advice to keep your skin healthy and glowing.
July 2nd, 2025·
3 mins
How to Build a Skincare Routine That Actually Works: An Evidence-Based Guide
Book a virtual visit with a Tono Health dermatologist today to get a personalized plan that fits your goals and lifestyle.

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Why a Skincare Routine Matters

A daily skincare routine does more than keep your face clean—it helps prevent breakouts, slow signs of aging, and protect you from sun damage. But with so many products, it can feel confusing. In this guide, you’ll learn how to build a simple, effective skincare routine. According to the American Academy of Dermatology (AAD), healthy skin habits are the foundation of good skin at every age.

The 4 Basics of Skincare

Most people only need four simple steps:

  1. Cleanse – Wash away dirt and oil.
  2. Treat – Apply products like retinoids or antioxidants.
  3. Moisturize – Keep skin hydrated.
  4. Protect – Use sunscreen every day.

Let’s break down each step.

1. Cleansing

Why it matters

Cleansing removes dirt, oil, makeup, and pollution. Without cleansing, your pores can get clogged, leading to breakouts.

How to do it

  • Wash twice daily—morning and night.
  • Use a gentle cleanser that doesn’t strip your skin.
  • Avoid hot water; lukewarm is best.

According to the AAD, harsh scrubbing can damage your skin barrier. Tip: If you have acne-prone skin, pick a cleanser with salicylic acid or benzoyl peroxide.

2. Treating with Active Ingredients

This is where you tackle your specific skin goals, such as:

  • Acne
  • Dark spots
  • Fine lines

Let’s look at evidence-based options:

Retinoids (Vitamin A Derivatives)

What they do

  • Speed up skin renewal
  • Boost collagen
  • Clear acne

The New England Journal of Medicine reports retinoids are the most proven anti-aging and acne treatment.

How to use

  • Start slowly (every other night).
  • Use a pea-sized amount.
  • Always apply sunscreen in the morning (retinoids make skin sensitive to sun).

Vitamin C

What it does

  • Brightens skin
  • Fades dark spots
  • Protects against UV damage

Studies in the British Journal of Dermatology confirm vitamin C reduces pigmentation over time.

How to use

  • Apply in the morning before moisturizer.
  • Store in a dark bottle to keep it fresh.

Niacinamide

What it does

  • Reduces redness
  • Calms acne
  • Strengthens the skin barrier

This is a good beginner ingredient that pairs well with other treatments.

3. Moisturizing

Why it matters

Moisturizer keeps your skin’s barrier strong, preventing dryness and irritation.

How to pick a moisturizer

  • Oily skin: Use a lightweight gel or lotion.
  • Dry skin: Use a thicker cream with ceramides or hyaluronic acid.
  • Sensitive skin: Look for fragrance-free formulas.

According to AAD recommendations, applying moisturizer while skin is damp helps lock in hydration.

4. Sun Protection

Why it matters: Sunscreen is your most important anti-aging product. It protects against UV rays that cause:

  • Wrinkles
  • Sunspots
  • Skin cancer

The NEJM published striking photos showing how sun exposure ages skin over time.

How to use:

  • Apply a broad-spectrum SPF 30+ every morning.
  • Reapply every 2 hours if outside.
  • Use even on cloudy days.

Tip: Mineral sunscreens with zinc oxide are best for sensitive skin.

Putting It All Together: Your Daily Routine

Here’s an example simple routine:

Morning

  1. Gentle cleanser
  2. Vitamin C serum
  3. Moisturizer
  4. Sunscreen SPF 30+

Night

  1. Gentle cleanser
  2. Retinoid (or other treatment)
  3. Moisturizer

Extra Tips for Healthy Skin

  • Be consistent—results take weeks to months.
  • Don’t overdo it—too many products can irritate.
  • Stay hydrated—drink water to support skin health.
  • Eat a balanced diet—vitamins help your skin renew itself.
  • Get enough sleep—your skin repairs itself overnight.

How Teledermatology Can Help

If you feel stuck or want guidance, teledermatology makes expert care easy:

  • Upload photos of your skin.
  • Share your current products.
  • Get a personalized plan from a dermatologist.
  • Receive prescriptions for retinoids, acne treatments, or other medications.
  • Follow up virtually to track progress.

According to the American Academy of Dermatology, virtual care is effective for most common skin concerns.

Final Takeaways

  • Cleansing, treating, moisturizing, and protecting form the core of an effective routine.
  • Stick to evidence-based ingredients like retinoids, vitamin C, and SPF.
  • Be patient—great skin takes consistency.
  • Teledermatology is a simple way to get expert help without leaving home.

Ready for Healthier Skin?

Book a virtual visit with a Tono Health dermatologist today to get a personalized plan that fits your goals and lifestyle.

Book Appointment

References

This article is for informational purposes only. If you are experiencing a medical emergency, visit an ER or call 911 right away.

Brian HaynesBrian Haynes is the Chief of Staff at Tono Health.

About the author

Brian Haynes is a product and strategy leader with over a decade of experience building and scaling technology solutions at Deloitte, Amazon, Meta, and Bank of America. He brings expertise in operational transformation, product management, and platform growth, having led cross-functional teams to deliver software and services used by millions of users and thousands of businesses. As Chief of Staff at Tono Health, Brian leverages his experience to execute strategic initiatives, accelerate growth, and expand access to high-quality virtual specialty care in dermatology, allergy, and endocrinology.